Shipping is calculated in checkout
51059-44-0
≥98%
A solid
460.4
5-hydroxy-8-methoxy-4-oxo-2-phenyl-4h-1-benzopyran-7-yl β-d-glucopyranosiduronic acid, wogonin 7-o-β-d-glucuronide, wogonin 7-β-d-glucuronide
- Data sheet: View or download
- MSDS: View or download
A flavonoid with anti-inflammatory and anticancer activities; an active metabolite of wogonin; decreases colonic pathological damage and myeloperoxidase and iNOS activity, as well as inhibits NF-κB and NLRP3 inflammasome activation in a DSS-induced mouse model of colitis at 25 and 50 mg/kg; inhibits phosphorylation of mTOR, as well as inhibits the growth of (IC50 = 133.9 µM), and induces autophagy in, MDA-MB-231 breast cancer cells; inhibits tube formation by HUVECs, increases Wnt3a levels and β-catenin phosphorylation in MCF-7 cells at 50-100 µM; reduces tumor growth and angiogenesis in an MCF-7 mouse xenograft model at 80 mg/kg
-20°C
