£156.00
Estimated delivery Wed 22 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
90780-52-2
Purity:
≥98%
Formulation:
A solution in ethanol
Molecular Weight:
344.5
Alternative Names:
(±)17-hydroxy-4z,7z,10z,13z,15e,19z-docosahexaenoic acid, (±)17-hdohe, 17-hydroxy docosahexaenoic acid, 17-hydroxy dha
- Data sheet: View or download
- MSDS: View or download
Product Description:
(±)17-HDHA is an autoxidation product of DHA in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} 17(S)-HDHA can be produced by enzymatic oxidation of DHA using soybean LO and is the putative product of mammalian 15-LOs.{7492} 17(S)-HDHA is an inhibitor of U-46619-induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 µM, respectively.{7481} (±)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA.
Storage Temperature:
-20°C