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490-79-9
≥98%
A crystalline solid
154.1
2,5-dihydroxy-benzoic acid, 5-hydroxysalicylic acid, carboxyhydroquinone, nsc 27224, nsc 49098, nsc 78825
A benzoic acid with diverse biological activities; decreases radiation-induced production of TBARS, hydrogen peroxide, and protein carbonyls, increases superoxide dismutase activity, and prevents hemolysis in isolated human erythrocytes from 5-100 µM; inhibits LDL oxidation and formation of cholesterol ester hydroperoxides in isolated human plasma from 1-10 µM; induces relaxation of isolated guinea pig trachea (EC50 = 20 µM); reduces cardiac hypertrophy and fibrosis and pulmonary remodeling, suppresses the renin-angiotensin-aldosterone system, and inhibits cardiac dysfunction in a mouse model of transverse aortic constriction-induced cardiac hypertrophy at 10 and 100 mg/kg; prevents cardiovascular collapse and lactic acidemia in a canine model of P. aeruginosa-induced septic shock
-20°C
