Bisindolylmaleimide I
Catalogue number:
CAY13298-5 mg
Supplier:
Size:
5 mg
Product is available in:
£112.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
133052-90-1
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
412.5
Alternative Names:
3-[1-[3-(dimethylamino)propyl]-1h-indol-3-yl]-4-(1h-indol-3-yl)-1h-pyrrole-2,5-dione, bim i, gf 109203x, gö 6850
- Data sheet: View or download
- MSDS: View or download
Product Description:
A highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM); competitive inhibitor for the ATP binding site of PKC; highly selective for PKCα, β1, β2, γ, δ, and ε isozymes; inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM); competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM
Storage Temperature:
-20°C
