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Imatinib (mesylate)

Catalogue number:
CAY13139-25 mg
25 mg _$$_
Product is available in:
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£39.00 Estimated delivery Tue 25 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:





A crystalline solid

Molecular Weight:


Alternative Names:

4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide, monomethanesulfonate, cgp57148b, sti-571

Product Description:

An inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit; inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 µM, respectively); inhibits the proliferation of Bcr-Abl-dependent R10(–) cells (IC50s = ~35-40 nM) and HMC-1 cells expressing constitutively active c-Kit in a concentration-dependent manner; prolongs survival in a mouse model of chronic myeloid leukemia at 100 mg/kg twice daily; inhibits replication of MERS-CoV and SARS-CoV in Vero E6 cells at 25 and 50 µM; reduces viral titers in IBV-infected Vero cells at 10 µM

Storage Temperature:


CAY13139-25 mg: Imatinib (mesylate)
CAY13139-25 mg: Imatinib (mesylate)
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