Prostaglandin E1
Catalogue number:
CAY13010-1 mg
Supplier:
Size:
1 mg
Product is available in:
£29.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
745-65-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
354.5
Alternative Names:
11α,15s-dihydroxy-9-oxo-prost-13e-en-1-oic acid, alprostadil, nsc 165559, pge1
- Data sheet: View or download
- MSDS: View or download
Product Description:
A vasoactive prostaglandin and an active metabolite of DGLA; an agonist of EP1, EP2, EP3, EP4, and IP receptors (Kis = 36, 10, 1.1, 2.1, and 33 nM, respectively, for the mouse receptors); inhibits ADP-induced platelet aggregation of isolated human platelet-rich plasma (IC50 = 40 nM) and isoproterenol-induced increases in ICa in isolated rabbit atrial cells (EC50 = 27 nM); induces vasodilation in isolated rat aortic rings and activates KATP in a cell-attached patch clamp assay using isolated rat VSMCs at 100 nM; decreases femoral arterial perfusion pressure in dogs
Storage Temperature:
-20°C