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15-deoxy-Δ12,14-Prostaglandin D2

Catalogue number:
CAY12700-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
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£247.00 Estimated delivery Wed 15 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

85235-11-6

Purity:

≥95%

Formulation:

A solution in methyl acetate

Molecular Weight:

334.5

Alternative Names:

9α-hydroxy-11-oxo-prosta-5z,12e,14e-trien-1-oic acid, 15-deoxy-δ12,14-pgd2

Product Description:

A metabolite of PGD2 and an agonist of DP2; binds DP2 (Ki = 50 nM) and induces activation of eosinophils (EC50 = 8 nM); induces PPARγ-mediated transcription in a reporter assay at 5 µM; cytotoxic to L1210 murine leukemia cells (IC50 = 0.3 µg/ml); inhibits ADP-induced platelet aggregation (IC50 = 320 ng/ml) less potently than PGD2

Storage Temperature:

-20°C

CAY12700-1 mg: 15-deoxy-Δ12,14-Prostagla
CAY12700-1 mg: 15-deoxy-Δ12,14-Prostaglandin D2
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