www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

11-deoxy-11-methylene Prostaglandin D2

Catalogue number:
CAY12410-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£93.00 Estimated delivery Tue 25 Jun
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

100648-29-1

Purity:

≥98%

Formulation:

A solution in methyl acetate

Molecular Weight:

350.5

Alternative Names:

9α,15s-dihydroxy-11-methylene-prosta-5z,13e-dien-1-oic acid, 11-deoxy-11-methylene pgd2

Product Description:

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase.{9588} PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin.{7894} However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay.{11175} The CRTH2-receptor actions of 11-deoxy-11-methylene PGD2 are not yet reported.

Storage Temperature:

-20°C

CAY12410-1 mg: 11-deoxy-11-methylene Pro
CAY12410-1 mg: 11-deoxy-11-methylene Prostaglandin D2
Details Cat number & supplier Size Price
5-trans Prostaglandin D2 CAY12210-5 mg · Cayman Chemical
CAY12210-5 mg
Cayman Chemical
5 mg £343.00
5 mg
view
11-deoxy-11-methylene Prostaglandin D2 CAY12410-10 mg · Cayman Chemical
CAY12410-10 mg
Cayman Chemical
10 mg £719.00
10 mg
view
5-trans Prostaglandin D2 CAY12210-10 mg · Cayman Chemical
CAY12210-10 mg
Cayman Chemical
10 mg £607.00
10 mg
view
11-deoxy-11-methylene Prostaglandin D2 CAY12410-5 mg · Cayman Chemical
CAY12410-5 mg
Cayman Chemical
5 mg £406.00
5 mg
view
5-trans Prostaglandin D2 CAY12210-1 mg · Cayman Chemical
CAY12210-1 mg
Cayman Chemical
1 mg £80.00
1 mg
view
BW A868C CAY12060-5 mg · Cayman Chemical
CAY12060-5 mg
Cayman Chemical
5 mg £498.00
5 mg
view
BW A868C CAY12060-10 mg · Cayman Chemical
CAY12060-10 mg
Cayman Chemical
10 mg £882.00
10 mg
view
BW A868C CAY12060-1 mg · Cayman Chemical
CAY12060-1 mg
Cayman Chemical
1 mg £113.00
1 mg
view
EUK 124 CAY12500-10 mg · Cayman Chemical
CAY12500-10 mg
Cayman Chemical
10 mg £95.00
10 mg
view
BW 246C CAY12055-5 mg · Cayman Chemical
CAY12055-5 mg
Cayman Chemical
5 mg £306.00
5 mg
view