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480-11-5
≥98%
A solid
284.3
5,7-dihydroxy-6-methoxy-2-phenyl-4h-1-benzopyran-4-one, 6-methoxybaicalein
- Data sheet: View or download
- MSDS: View or download
A flavonoid with diverse biological activities; inhibits poly(I:C)-induced decreases in cell viability and increases in NO production in RAW 264.7 macrophages at 5-25 µM; inhibits poly(I:C)-induced increases in IL-1α, IL-1β, GM-CSF, IL-6, IL-10, MCP-1, and TNF-α production in RAW 264.7 cells at 10-50 µM; inhibits hypoxia-induced migration and invasion of MCF-7, DU145, and HepG2 cells in wound healing and cell invasion assays, respectively, at 10 and 20 µM; an inhibitor of UGT1A1 (IC50 = 9.14 µM) and P-glycoprotein (IC50 = 78.3 µM); increases the cytotoxicity of the P-glycoprotein substrate paraquat in MDR1-MDCKII cells and paclitaxel in MX-1 and MX-1/T cells
-20°C
