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50-28-2
≥98%
A crystalline solid
272.4
estra-1,3,5(10)-triene-3,17β-diol, 17β-oestradiol, e2, estradiol, β-estradiol
- Data sheet: View or download
- MSDS: View or download
The major pre-menopausal bioactive estrogen and an active metabolite of testosterone; binds to estrogen receptors localized to the nucleus, cytoplasm, and plasma membrane and induces gene transcription or non-genomic intracellular signaling in a location-dependent manner; regulates reproductive development in females and spermatogenesis in males, as well as various non-reproductive processes including lipid and glucose homeostasis, bone mass maintenance, cognition, energy balance, and dilation of blood vessels; deficiency is associated with fatigue, incontinence, osteoporosis, depression, emotional instability, and hot flashes
-20°C