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Human CellExp™ MMP-3, Human Recombinant

Supplier:
Catalogue number:
P1310-10
Size:
10 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£441.00 Estimated delivery Wed 21 Apr
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MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyses natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk . MMP-3 hydrolyses components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta.

Product Type:

Proteins and peptides

Alternative Names:

Stromelysin-1, EC 3.4.24.17, Matrix metalloproteinase-3, MMP-3, Transin-1, SL-1, STMY, STR1, STMY1, MGC126102, MGC126103, MGC126104

Storage Temp:

-20°C

Molecular Weight:

52

UNSPSC Code:

12352202