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Anti-CFTR Antibody (SPM176)

Supplier:
Catalogue number:
A1575-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£505.00 Estimated delivery Wed 28 Apr
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This mAb recognises a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Product Type:

Antibodies

Species Reactivity:

Human and Mouse

Storage Temp:

-20°C

Antibody Host:

Mouse

Antibody Isotype:

Mouse / IgG2a

Formulation:

Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Antibody Type:

Monoclonal

Clone Number:

SPM176

UNSPSC Code:

12352203

Anti-CFTR Antibody (SPM176)

Anti-CFTR Antibody (SPM176)