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XL-647 is an orally bioavailable small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. It binds to and inhibits several receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularisation, including epidermal growth factor receptor (EGFR, ERBB1), epidermal growth factor receptor 2 (HER2, ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4).
Product Type:
Biochemicals
CAS Number:
781613-23-8
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
491.38
UNSPSC Code:
12352200
