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STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC₅₀ = 625 nM). STF-62247 induces cytotoxicity and reduces tumor growth of VHL-deficient RCC cells compared to genetically matched cells with wild-type VHL.
Product Type:
Biochemicals
CAS Number:
315702-99-9
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
267.35
UNSPSC Code:
12352200
