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Sivelestat

Supplier:
Catalogue number:
B2144-25
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£428.00 Estimated delivery Wed 28 Apr
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Sivelestat (ONO-5046) is a potent neutrophil elastase inhibitor. It acts as a substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC₅₀ = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Sivelestat displays >100-fold greater selectivity over pancreatic elastase (IC₅₀ = 5.6 µM). It does not inhibit trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G even at concentrations as high as 100 µM.

Product Type:

Biochemicals

CAS Number:

127373-66-4

Storage Temp:

-20°C

Compound Purity:

≥97% by HPLC

Molecular Weight:

434.46

UNSPSC Code:

12352200

Sivelestat

Sivelestat