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Estimated delivery Wed 15 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
77-67-8
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
141.2
Alternative Names:
3-ethyl-3-methyl-2,5-pyrrolidinedione, ci-366, nsc 64013
- Data sheet: View or download
- MSDS: View or download
Product Description:
An anticonvulsant; increases glucose, fructose-1,6-bisphosphate, and pyruvate levels in rat brain at 200 mg/kg; reduces the severity of audiogenic seizures in a rat model of barbiturate withdrawal-induced convulsions at 400 mg/kg; inhibits PTZ- or brainstem stimulation-induced tonic hindlimb extension (ED50s = 35 and 70 mg/kg, respectively), as well as leptazol-induced clonic seizures (ED50 = 230 mg/kg), in rats; reduces resting tremor by 60% in a macaque model of Parkinson's disease induced by MPTP when administered at a dose of 150 mg/animal
Storage Temperature:
-20°C
