£91.00
Estimated delivery Fri 29 Mar
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
30652-11-0
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
139.2
Alternative Names:
3-hydroxy-1,2-dimethyl-4(1h)-pyridinone, cgp 37391, dn 18001af
- Data sheet: View or download
- MSDS: View or download
Product Description:
An iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities; reverses erastin-induced ferroptosis in HT-1080 fibrosarcoma cells at 100 µM; reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively; reduces cholesterol diet-induced increases in the levels of Aβ42, Aβ40, and the phosphorylation of tau and GSK-3β in the rabbit hippocampus at 50 mg/kg
Storage Temperature:
-20°C