Pomalidomide
Catalogue number:
CAY19877-5 mg
Supplier:
Size:
5 mg
Product is available in:
£89.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
19171-19-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
273.2
Alternative Names:
4-amino-2-(2,6-dioxo-3-piperidinyl)-1h-isoindole-1,3(2h)-dione, 3-amino thalidomide, cc-4047
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of cereblon (IC50 = ~3 µM for the human recombinant CRBN-DDB1 complex); inhibits autoubiquitination of CRBN in HEK293T cells expressing CRBN; inhibits proliferation of U266 myeloma cells at 0.1-10 µM; reduces tumor growth in a H929 R10-1 lenalidomide-resistant mouse xenograft model at 3 mg/kg per day when used in combination with dexamethasone
Storage Temperature:
-20°C
