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R-568

Catalogue number:
CAY17415-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£913.00 Estimated delivery Wed 1 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

177172-49-5

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

340.3

Alternative Names:

2-chloro-n-[(1r)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine, monohydrochloride, krn 568, nps r-568, tecalcet

Product Description:

A calcimimetic and positive allosteric modulator of CaSR; potentiates extracellular calcium-induced increases in intracellular calcium release and inhibits the secretion of PTH (IC50 = 27 nM) in bovine parathyroid cells; decreases PTH and plasma calcium levels in rats (ED50s = 1.1 and 10.4 mg/kg, respectively); suppresses parathyroid cell proliferation in a rat model of chronic renal insufficiency at 15 mg/kg

Storage Temperature:

-20°C

CAY17415-50 mg: R-568
CAY17415-50 mg: R-568
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