4’-hydroxy Tamoxifen
Catalogue number:
CAY19519-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
£665.00
Estimated delivery Fri 10 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
82413-23-8
Purity:
≥98% (may contain up to 10% of the (E) isomer)
Formulation:
A crystalline solid
Molecular Weight:
387.5
Alternative Names:
4-[(1z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-phenol
- Data sheet: View or download
- MSDS: View or download
Product Description:
An ER antagonist and active metabolite of tamoxifen (IC50 = 2.4 nM for the rabbit receptor); inhibits the proliferation of MCF-7 and MDA-MB-231 cells (IC50s = 27 and 16 µM, respectively); reduces the survival percentage of HEC-1B and HEC-1A cells at 10 and 100 nM; administration of liposomes encapsulating 4'-hydroxy tamoxifen (4 mg/kg twice per week) reduces tumor growth in an RPMI-8226 multiple myeloma mouse xenograft model
Storage Temperature:
-20°C
