£42.00
Estimated delivery Fri 17 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
106941-25-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
273.2
Alternative Names:
p-[[2-(6-amino-9h-purin-9-yl)ethoxy]methyl]-phosphonic acid, gs-0393, pmea
- Data sheet: View or download
- MSDS: View or download
Product Description:
An active metabolite of adefovir dipivoxil; formed from adefovir dipivoxil by CES2; inhibits cytopathogenicity induced by HSV-1 and HSV-2 (EC50 = 7 µg/ml for both in E6SM cells), HIV-1 and HIV-2 (EC50s = 1.8 and 2.5 µg/ml, respectively, in CEM cells), and VZV (EC50 = 10 µg/ml in human embryonic lung fibroblasts); reduces increases in lymph node viral DNA and serum IgG levels in a mouse model of AIDS induced by infection with LP-BM5 at 50 mg/kg; inhibits tumor growth induced by MSV infection in mice at 50 mg/kg
Storage Temperature:
-20°C
