GW-7647 - 9571-5 - 5 mg - BioVision - small molecule compounds
GW-7647
Catalogue number:
9571-5
Name:
GW-7647
Supplier:
Availability:
GW-7647 is a potent, selective agonist of human and murine PPARα. It activates human PPARα, PPARγ, and PPARδ with EC₅₀ values of 0.006, 1.1 and 6.2 µM, respectively, in a GAL4-PPAR binding assay. Similar EC₅₀ values of 0.001, 1.3, and 2.9 were observed with the murine receptors. Modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules in vitro. Has lipid-lowering effects following oral administrationin vivo. Reduces NO production in macrophages, exhibits anti-inflammatory properties.
Data sheet:
Product Type:
Small Molecule Compounds
CAS Number:
265129-71-3
Alternative Names:
2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
502.75
UNSPSC Code:
12352100
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