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Bacterial Sortase Substrate III, Abz/DNP

Supplier:
Catalogue number:
ANA63717
Size:
1 mg
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The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonisation-associated surface proteins to the cell wall. SrtA selectively recognises a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this FRET substrate can be monitored at Ex/Em=320 nm/420 nm.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

928

Reference:

Bentley, M. et al. J. Biol. Chem. 282, 6571 (2007).

UNSPSC Code:

12352202