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SMAD3 Inhibitor, SIS3

Catalogue number:
CAY15945-500 ug
Supplier:
Size:
500 µg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£85.00 Estimated delivery Wed 1 May
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1009104-85-1

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

453.5

Alternative Names:

1-(3,4-dihydro-6,7-dimethoxy-2(1h)-isoquinolinyl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one

Product Description:

A selective inhibitor of TGF-β and activin signaling that suppresses SMAD3 phosphorylation (IC50 = 3 µM); reduces TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts

Storage Temperature:

-20°C

CAY15945-500 ug: SMAD3 Inhibitor, SIS3
CAY15945-500 ug: SMAD3 Inhibitor, SIS3
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