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Fmoc-Lys(N3)-OH

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Catalogue number:
ANA53100-F025
Size:
250 mg
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An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) for the synthesis of side-chain modified peptides and proteins.1 The side-chain azido (N3) group is stable in trifluoroacetic acid (TFA) or piperidine (Pip), two reagents commonly used in SPPS. The azido group can be readily converted to an amine on the solid phase or in solution via the Staudinger reduction.2

Product Type:

Reagents & Kit Components

CAS Number:

159610-89-6

Storage Temp:

4°C

Compound Purity:

≥95% by HPLC

Molecular Weight:

394.42

Reference:

1. Vallee, M. R. J.; Majkut, P.; Wilkening, C. W.; Muller, G.; Hackenberger, C. P. R. Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins.Org. Lett. 2011 (13) 5440-5443. 2. Staudinger, H.; Meyer, J. UberneueorganischePhosphorverbindungen III. Phosphinmethylenederivative und Phosphinimine. Helvetica Chim. Acta. 1919 (2) 635-646.

UNSPSC Code:

12352209

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