£72.00
Estimated delivery Tue 7 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
404950-80-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
349.4
Alternative Names:
(2e)-n-hydroxy-3-[4-[[[2-(2-methyl-1h-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide, lbh-589
- Data sheet: View or download
- MSDS: View or download
Product Description:
A pan-HDAC inhibitor (Kis = 0.6-31 nM for HDAC1-11); inhibits growth in a panel of 37 human or mouse lung cancer cell lines, including SCLC, NSCLC, and mesothelioma cells (IC50s = 4-175, 5-310, and 5-470 nM, respectively); induces tumor regression in BK-T and RG-1 SCLC mouse xenograft models at 20 mg/kg i.p.
Storage Temperature:
-20°C