£299.00
Estimated delivery Fri 17 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
191732-72-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
259.3
Alternative Names:
3-(4-amino-1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-piperidinedione, cc-5013
- Data sheet: View or download
- MSDS: View or download
Product Description:
A derivative of thalidomide; reduces TNF-α production in isolated human PBMCs and whole blood stimulated by LPS from S. minnesota (IC50s = 13 and 25 nM, respectively); has been used as a building block in the synthesis of PROTACs that induce the degradation of IKZF1 and IKZF3 in MM.1S cells; reduces vascularization and total microvascular length in a rat mesenteric window assay model at 250 mg/kg per day, p.o.
Storage Temperature:
-20°C
