£567.00
Estimated delivery Tue 14 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
144060-53-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
316.4
Alternative Names:
2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid, fbx, tei 6720, tmx 67
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of xanthine oxidase; inhibits bovine milk xanthine oxidase as well as mouse and rat liver xanthine oxidase/xanthine dehydrogenase (IC50s = 1.4, 1.8, and 2.2 nM, respectively); decreases serum urate levels in a potassium oxonate rat model of hyperuricemia (ED50 = 1.5 mg/kg); reduces hepatic macrovesicular steatosis in mice fed a high-fat diet containing trans fatty acids at 1 mg/kg per day; increases CNS expression of GOT2 and improves neurological symptoms in a mouse model of secondary progressive EAE
Storage Temperature:
-20°C