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Memantine (hydrochloride)

Supplier:
Catalogue number:
CAY14184-25 mg
Size:
25 mg
Product is available in:
  • UK
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£50.00 Estimated delivery Thu 30 Sep
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An NMDA receptor antagonist; blocks NMDA-induced currents in rat retinal ganglion cells by 90% at 12 µM; reverses I1PP2A-induced inhibition of dephosphorylation of tau194-207 in vitro; restores PP2A activity, decreases GSK-3β and Aβ levels in the hippocampus, cerebral cortex, and ventricular areas, and attenuates spatial learning and memory in the AAV1-I1PP2A rat model of Alzheimer's disease at 2 mg/kg; reduces responding on the ethanol-associated lever in a cue-induced ethanol seeking test in rats at 20 mg/kg; decreases secretion of MMP-9, degradation of collagen IV, the size of cerebral ischemia-induced brain infarcts, and neuronal cell death in a mouse model of focal cerebral ischemia

Product Type:

Biochemicals

CAS Number:

41100-52-1

Alternative Names:

3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride, akatinol, axura, ebix, namenda, nsc 102290, sun y7017

Storage Temp:

22°C

Formulation:

A crystalline solid

Compound Purity:

≥98%

Formula:

C12H21N • HCl

UNSPSC Code:

12352202

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