(S)-Pramipexole (hydrochloride)
Catalogue number:
CAY11981-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
£121.00
Estimated delivery Wed 8 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
104632-25-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
284.2
Alternative Names:
(6s)-4,5,6,7-tetrahydro-n6-propyl-2,6-benzothiazolediamine, dihydrochloride, (–)-pramipexole
- Data sheet: View or download
- MSDS: View or download
Product Description:
A dopamine D2S, D2L, D3, and D4 receptor agonist (EC50s = 426.58, 338.84, 2.24, and 128.82 nM, respectively, in a [35S]GTPγS binding assay); a partial agonist of α2A-ARs (EC50 = 3,548.13 nM); selective for dopamine D2-4 receptors (Kis = 954.99, 1,698.24, 12.59, 128.82 nM for for D2S, D2L, D3, and D4 receptors, respectively, in a radioligand binding assay) over D1 and D5 receptors (Kis = >10,000 nM for both); prevents MPTP-induced decreases in the number of dopaminergic neurons in the substantia nigra pars compacta in common marmosets at 60 µg/kg per day before, during, and after administration of MPTP
Storage Temperature:
-20°C
