£220.00
Estimated delivery Tue 14 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1144035-53-9
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
478.3
Alternative Names:
4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-(3,5-dichlorophenyl)methyl ester-1-piperazinecarboxylic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of autotaxin (IC50 = 2.8 nM in an enzyme assay); reverses leptin-induced MMP-13 expression in human OA chondrocytes at 10 µM; reduces LPA production by >95% following carrageenan-induced inflammation in rats at 30 mg/kg; inhibits autotaxin activity in human whole blood (IC50 = 101 nM)
Storage Temperature:
-20°C
