£280.00
Estimated delivery Tue 7 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
337349-54-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
383.5
Alternative Names:
2-[[3,4,5,6,7,8-hexahydro-3-(4-methoxyphenyl)-4-oxo[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-acetonitrile, nec-5
- Data sheet: View or download
- MSDS: View or download
Product Description:
A RIP1 kinase inhibitor; inhibits phosphorylation of RIP1 in Jurkat cells at 10 and 30 µM; inhibits TNF-α-induced necroptosis in FADD-deficient Jurkat cells (EC50 = 0.24 µM); reduces LDH release in S. marcescens-infected MH-S macrophages; improves survival in a mouse model of S. marcescens-induced pneumonia at 100 µM, i.p.
Storage Temperature:
-20°C