FC, IHC-FS, ICC
Acute myelogenous leukemia cell line KG-1
NCAM, neural cell adhesion molecule, Leu-19, NKH1
CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.
2 - 8°C