Multidrug Resistance Assay Kit (Calcein AM)
Catalogue number:
CAY600370-1,000 tests
Supplier:
Size:
1000 tests _$$_
Product is available in:
£341.00
Estimated delivery Tue 14 May
Shipping is calculated in checkout
Shipping is calculated in checkout
Product Description:
Cayman's Multidrug Resistance Assay Kit provides a convenient tool for studying the modulation of cellular multidrug resistance (MDR) machinery. The kit employs calcein AM, a cell-permeable nonfluorescent dye, which is cleaved intracellularly to yield the impermeant fluorescent molecule, calcein. This calcein is rapidly excluded from cells expressing the MDR proteins P-gp or MRP, and so functions as a probe for the detection of chemical compounds inhibiting MDR proteins. Propidium iodide is provided as a stain for marking dead or damaged cells. Cyclosporin A, a competitive inhibitor of MDR proteins, and verapamil, a noncompetitive inhibitor, are included as controls.
Storage Temperature:
-20°C
