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6-Thioguanosine-5'-O-triphosphate (sodium salt)

Catalogue number:
CAY38390-2.7 mg
Supplier:
Size:
2.7 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£418.00 Estimated delivery Wed 3 Jul
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:

≥98%

Formulation:

A solution in water

Molecular Weight:

627.2

Alternative Names:

6-thio-guanosine 5′-(tetrahydrogen triphosphate), tetrasodium salt, 6-thio-gtp

Product Description:

An active metabolite of 6-thioguanine and azathioprine; binds to a variety of GTPases but selectively inhibits activation of Rac1 and Rac2 over Cdc42 in primary human CD4+ T cells stimulated with anti-CD3 and anti-CD28 antibodies; inhibits T cell receptor-stimulated proliferation of T cells and reduces CD28-dependent T cell survival in vitro in isolated mouse splenocytes; increases survival in a mouse model of heart transplantation at 0.5 mg/kg

Storage Temperature:

-80°C

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Azathioprine CAY13987-1 g · Cayman Chemical
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6-Thioguanine CAY15774-1 g · Cayman Chemical
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Guanosine 5'-[γ-thio]triphosphate (sodium salt) CAY38565-2.7 mg · Cayman Chemical
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