YM-155 (chloride)
Catalogue number:
CAY36827-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£117.00
Estimated delivery Wed 8 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
355406-09-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
398.8
Alternative Names:
4,9-dihydro-3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(2-pyrazinylmethyl)-1h-naphth[2,3-d]imidazolium, monochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A survivin inhibitor; inhibits survivin promoter activity in a reporter assay (IC50 = 0.54 nM); reduces survivin levels and induces apoptosis in PC3 and PPC-1 prostate cancer cells from 10-1,000 nM; inhibits tumor growth, decreases intratumor survivin levels, and induces tumor regression in a PC3 mouse xenograft model at 3 and 10 mg/kg; inhibits SARS-CoV-2 PLpro (IC50 = 2.47 µM) and reduces the number of viral RNA copies in SARS-CoV-2-infected Vero E6 cells
Storage Temperature:
-20°C