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SR 57227A (hydrochloride)

Catalogue number:
CAY35499-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£765.00 Estimated delivery Fri 3 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

77145-61-0

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

248.2

Alternative Names:

1-(6-chloro-2-pyridinyl)-4-piperidinamine, monohydrochloride

Product Description:

A 5-HT3 receptor agonist; selectively binds 5-HT3 receptors (IC50 = 2.8 nM) over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2, and 5-HT4 receptors (IC50s = >1,000 nM for all); induces contractions in isolated guinea pig ileum at 20 µM; intrastriatal administration induces contralateral turning behavior in mice at 1 µg/animal; reduces immobility time in the forced swim test in rats (ED50 = 7.6 mg/kg); reduces the number of escape failures in a rat model of learned helplessness and the duration of fighting in a mouse model of isolation-induced aggression

Storage Temperature:

-20°C

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