SR 57227A (hydrochloride)
Catalogue number:
CAY35499-50 mg
Supplier:
Size:
50 mg
Product is available in:
£765.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
77145-61-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
248.2
Alternative Names:
1-(6-chloro-2-pyridinyl)-4-piperidinamine, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A 5-HT3 receptor agonist; selectively binds 5-HT3 receptors (IC50 = 2.8 nM) over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2, and 5-HT4 receptors (IC50s = >1,000 nM for all); induces contractions in isolated guinea pig ileum at 20 µM; intrastriatal administration induces contralateral turning behavior in mice at 1 µg/animal; reduces immobility time in the forced swim test in rats (ED50 = 7.6 mg/kg); reduces the number of escape failures in a rat model of learned helplessness and the duration of fighting in a mouse model of isolation-induced aggression
Storage Temperature:
-20°C