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COH000

Catalogue number:
CAY34906-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£466.00 Estimated delivery Tue 4 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1534358-79-6

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

419.5

Alternative Names:

(1r,4s)-1-[(1r)-2-(4-methylphenyl)-1-(phenylamino)ethyl]-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2,3-dimethyl ester

Product Description:

An inhibitor of SUMO-activating enzyme (IC50 = 0.2 µM); selective for this enzyme over UAE and NAE at 10 µM; induces degradation of SAE2 in HCT116 human colon cancer cells; induces intratumoral apoptosis, decreases intratumoral c-Myc expression, and reduces tumor growth in an HCT116 mouse xenograft model at 10 mg/kg

Storage Temperature:

-20°C

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