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Aldoxorubicin (hydrochloride)

Catalogue number:
CAY35311-25 mg
Supplier:
Size:
25 mg _$$_
Product is available in:
  • UK
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  • Rest of World
£343.00 Estimated delivery Tue 4 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

480998-12-7

Purity:

≥95%

Formulation:

A solid

Molecular Weight:

787.2

Alternative Names:

2,5-dihydro-2,5-dioxo-1h-pyrrole-1-hexanoic acid, 2-[1-[(2s,4s)-4-[(3-amino-2,3,6-trideoxy-α-l-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide, hydrochloride, doxo-emch, d

Product Description:

A prodrug form of doxorubicin; selectively binds to serum albumin, which releases doxorubicin in acidic environments, such as the tumor microenvironment; inhibits the proliferation of RenCa, MCF-7, and LXFL 529 cells (IC50s = 1, 1.1, and 0.5 µM, respectively); induces tumor regression in an MDA-MB-435 breast cancer mouse xenograft model at 39.3 µmol/kg; not toxic to mice unlike doxorubicin (LD50 = >60 mg/kg); has been used to conjugate doxorubicin to antibodies

Storage Temperature:

-20°C

Details Cat number & supplier Size Price
Doxorubicin (hydrochloride) CAY15007-10 mg · Cayman Chemical
CAY15007-10 mg
Cayman Chemical
10 mg £74.00
10 mg
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