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EMD 534085

Catalogue number:
CAY35719-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£713.00 Estimated delivery Fri 26 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

858668-07-2

Purity:

≥99%

Formulation:

A solid

Molecular Weight:

476.5

Alternative Names:

n-[2-(dimethylamino)ethyl]-n′-[[(2r,4as,5r,10bs)-3,4,4a,5,6,10b-hexahydro-5-phenyl-9-(trifluoromethyl)-2h-pyrano[3,2-c]quinolin-2-yl]methyl]-urea

Product Description:

An Eg5 inhibitor (IC50 = 8 nM); inhibits proliferation of HCT116 cells (IC50 = 30 nM); induces mitotic arrest and apoptosis in HL-60 cells; reduces tumor growth in a COLO 205 colon cancer mouse xenograft model at 15 and 30 mg/kg

Storage Temperature:

-20°C

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