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BMS-299897

Catalogue number:
CAY35777-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£147.00 Estimated delivery Fri 26 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

290315-45-6

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

511.9

Alternative Names:

2-[(1r)-1-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoro-benzenebutanoic acid

Product Description:

A γ-secretase inhibitor; selectively cleaves APP CTF over Notch-1 CTF in HEK293 cells (IC50s = 7.1 and 105.9 nM, respectively); reduces increases in Aβ42 levels induced by Aβ (25-35) in the mouse hippocampus at 0.1-1 nmol/animal; prevents deficits induced by Aβ (25-35) in the novel object recognition test when tested with a one-hour, but not a 24-hour, intertrial interval

Storage Temperature:

-20°C

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