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S,S-hydroxy Bupropion (hydrochloride)

Catalogue number:
CAY35718-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£166.00 Estimated delivery Tue 30 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

106083-71-0

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

292.2

Alternative Names:

(2s,3s)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol, monohydrochloride, bupoh, bw 306u, gw 353162a, radafaxine

Product Description:

An active metabolite of bupropion; inhibits dopamine and norepinephrine but not 5-HT reuptake in HEK293 cells expressing the human transporters (IC50s = 0.63, 0.241, and >100 µM, respectively); an antagonist of α3β4-, α4β2-, α4β4-, and α1β1 subunit-containing nAChRs (IC50s = 11, 3.3, 30, and 28 µM, respectively); inhibits nicotine-induced analgesia in the tail-flick and hot plate tests, hyperlocomotion, and hypothermia in mice (ED50s = 0.2, 1, 0.9, and 1.5 mg/kg, respectively); substitutes for (+)-amphetamine in rats in a two-lever drug discrimination test (ED50 = 4.4 mg/kg)

Storage Temperature:

-20°C

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