Akuammine
Catalogue number:
CAY35149-5 mg
Supplier:
Size:
5 mg
Product is available in:
£601.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
3512-87-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
382.5
Alternative Names:
(2s,3e,7as,12as,12bs,15r)-3-ethylidene-1,3,4,6,7,12b-hexahydro-9-hydroxy-12-methyl-2h,12h-12a,2,7a-(epoxyethanylylidene)indolo[2,3-a]quinolizine-15-carboxylic acid, methyl ester, (-)-akuammine, vincamajoridine
- Data sheet: View or download
- MSDS: View or download
Product Description:
An indole alkaloid with analgesic activity; selectively binds the µ- and κ-opioid receptors over the δ-opioid receptor (Kis = 0.3, 1.68, and 10.4 µM for the human receptors, respectively); inhibits forskolin-induced cAMP production in HEK293 cells expressing human µ- or κ-opioid receptors (IC50s = 2.6 and 0.073 µM, respectively); increases the latency to withdrawal in the tail-flick or hot plate test in mice at 60 mg/kg
Storage Temperature:
-20°C