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Y-33075

Catalogue number:
CAY35108-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£102.00 Estimated delivery Fri 3 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

199433-58-4

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

280.3

Alternative Names:

4-[(1r)-1-aminoethyl]-n-1h-pyrrolo[2,3-b]pyridin-4-yl-benzamide, rki-983, snj-1656, y-39983

Product Description:

An inhibitor of ROCK2 (IC50 = 3.6 nM); selective for ROCK2 over PKC and CaMKII (IC50s = 420 and 810 nM, respectively); topical application reduces intraocular pressure in rabbit and cynomolgus monkeys at 0.05% v/v; increases axonal regeneration at the crush site in a cat model of surgically-induced optic nerve damage at 10 and 100 µM; inhibits demyelination and reduces the incidence of relapse episodes in a mouse model of chronic relapsing EAE

Storage Temperature:

-20°C

Details Cat number & supplier Size Price
Y-33075 (hydrochloride) CAY36216-25 mg · Cayman Chemical
CAY36216-25 mg
Cayman Chemical
25 mg £711.00
25 mg
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