£63.00
Estimated delivery Fri 24 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
500-92-5
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
253.7
Alternative Names:
n-(4-chlorophenyl)-n′-(1-methylethyl)-imidodicarbonimidic diamide, chlorguanide, chloroguanide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A prodrug form of cycloguanil; metabolized by CYP2C19 and CYP3A to form cycloguanil in human liver microsomes; active against chloroquine- and quinine-resistant strains of P. falciparum alone or in combination with atovaquone (EC50s = 0.22-2.67 and 0.37-1.6 µM, respectively); reduces parasitemia in a mouse model of P. berghei infection (MED = 32 mg/kg)
Storage Temperature:
-20°C