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BAY-678

Supplier:
Catalogue number:
B3061-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£224.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

BAY-678 is a potent, selective, cell-permeable inhibitor of human neutrophil elastase (HNE).The activity of HNE is increased in inflammatory diseases. BAY-678 shows Ki values of 15 nM and 600 nM for human and rat neutrophil elastase respectively and IC₅₀ of 20 nM in vitro. It shows beneficial pulmonary hemodynamic and vascular effects in animal models of pulmonary arterial hypertension. The S-enantiomer BAY-677 is a negative control for BAY-678.

Product Type:

Biochemicals

CAS Number:

675103-36-3

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

400.35

UNSPSC Code:

12352200

BAY-678

BAY-678

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