Gabexate mesylate
Catalogue number:
B3058-50
Supplier:
BioVision
Size:
50 mg _$$_
Product is available in:
N/A
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CAS Number:
56974-61-9
Purity:
≥97%
Molecular Weight:
417
Alternative Names:
FOY; Megacart; ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid; 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester mesylate; [Ethyl p-(6-guanidinohexanoyloxy) benzoate]methanesulfonate
- Data sheet: View or download
- MSDS: View or download
Product Description:
Gabexate is an inhibitor of serine proteases. It inhibits plasma kallikrein, thrombin, plasmin, factor Xa with Ki values of 0.2 µM, 0.97 µM, 1.6 µM and 8.5 µM. It exerts an anticoagulant effect on the clotting activity of thrombin. It inhibits LPS-induced TNF-alpha production in monocytes by inhibiting activation of both NF-kappaB and activator protein-1. It slightly inhibits SARS-CoV-2 S-driven host cell entry in lung cells.
Storage Temperature:
-20°C
