Ditolylguanidine
Catalogue number:
B3044-500
Supplier:
BioVision
Size:
500 mg _$$_
Product is available in:
N/A
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CAS Number:
97-39-2
Purity:
≥98%
Molecular Weight:
239
Alternative Names:
DTG; DOTG; 1,3-Di-o-tolylguanidine; 1,2-bis(2-methylphenyl)guanidine; {imino[(2-methylphenyl)amino]methyl}(2-methylphenyl)amine; 1,3-di-ortho-tolyl-guanidine
- Data sheet: View or download
- MSDS: View or download
Product Description:
Ditolylguanidine is a sigma receptor (σR) agonist with neuroprotective activity. It shows Kd values of 21.9 nM and 57.4 nM for σ2 and σ1 receptor respectively. Combined treatment with Ditolylguanidine (5 mg/kg) and memantine induces antidepressant-like effect in rats. Sigma receptor modulators are predicted to show activity against SARS-Cov-2, based on viral assay screens and interaction of the SARS-CoV-2 proteins Nsp6 and Orf9c with sigma receptors.
Storage Temperature:
-20°C
