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N4-Hydroxycytidine

Supplier:
Catalogue number:
B3039-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£77.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

N4-Hydroxycytidine is a ribonucleoside analog with broad-spectrum antiviral activity. The prodrug of N4-hydroxycytidine is EIDD-2801. N4-Hydroxycytidine is active against influenza, Ebola, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)and Venezuelan equine encephalitis virus (VEEV). It inhibits replication of SARS-CoV-2 and Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells with IC₅₀ values of 0.08 µM and 0.15 µM respectively. N4-Hydroxycytidine (100 and 400 mg/kg twice per day) reduces lung viral titers in a mouse model of Respiratory Syncytial Virus (RSV) infection.

Product Type:

Biochemicals

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

259.22

UNSPSC Code:

12352200

N4-Hydroxycytidine

N4-Hydroxycytidine

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