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Pretomanid (PA-824)

Supplier:
Catalogue number:
B3033-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£83.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Pretomanid is a nitroimidazopyran active againt Mycobacterium tuberculosis. It is active against multidrug-resistant M. tuberculosis clinical isolates with MIC <1 µg/ml. Pretomanid at 25, 50, and 100 mg/kg of body weight daily for 10 days or 60 days reduces the mycobacterial burden in both spleen and lung tissue in a mouse infection model. Pretomanid at 100 mg/kg in cyclodextrin/lecithin reduces the bacterial load below 500 CFU in the lungs and spleen. It is approved for use in combination treatment for drug-resistant, treatment-intolerant or non-responsive multidrug-resistant (MDR) Tuberculosis.

Product Type:

Biochemicals

CAS Number:

187235-37-6

Storage Temp:

-20°C

Compound Purity:

≥95%

Molecular Weight:

359.26

UNSPSC Code:

12352200

Pretomanid (PA-824)

Pretomanid (PA-824)

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